Wednesday, April 20, 2011

A Novel Treatment for Malaria

Estimates of noxious exhalation cases that occur annually round the world range between 250 million and 500 a thousand thousand of which over 90 percent are in sub-Saharan Africa. The chiefly vulnerable are young children under five, pregnant women and refugees in remote country areas. This high risk group accounts on the side of majority of deaths estimated annually round 2 million.

Synthetic mainline medications be under the necessity become largely ineffective due to trencher-friend resistance. Presently, Artemisinin Combination Therapies (ACTs) are the earliest line medication for treatment of malaria in majority of the countries. Several pharmaceutical companies desire produced various combinations using artemisinin or a single one one of its derivatives along through other anti-malarial synthetics. However, at offering the only source of the first anti-malarial (artemisinin) in the earth is the herbal plant Artemisia annua L., what one. has been used in its untired form for chills and fevers in China in opposition to over two thousand years.

Several organizations on every side the world are actively pursuing alternate solutions for treating and preventing malaria. An inexpensive cure for malaria has been developed using ~y out-of-the-box approach based forward the following rationale:

• Synthesized anti-malarials used for the time of the past 100 years or in this way were all first identified and detached from plant sources.

• Over the bygone time few years, synthesized versions used only have all become ineffective.

• Whereas, Cinchona yelp taken directly from the plant was used conducive to centuries round the world for management of malaria.

• Tea made from foliage of the Artemisia plant has been used in China for centuries.

• Since bio-chemical compounds inside of a plant material do not live in isolation, it would be be present to answer that extracting just the single composite from the whole plant material would negate the supportive synergistic importance of the co-existing compounds.

• It follows that a reparative based on whole of the settle material which contains the anti-malarial would exist appropriate.

• This anti-malarial plant bodily should be purified and concentrated to admit easy and optimal administration of the restoration to a patient.

• This effect could have existence largely improved by

Using newly developed agricultural and harvesting techniques to become greater the crop output and Artemisinin easy in mind in the plant to1.7-2.2 %. Note: Artemisinin make easy in the wild or cultivated Artemisia plants in China and Vietnam is surrounding 0.6-0.8%. Besides the menstrum extraction techniques widely used decrease the suitable artemisinin to 0.4 to 0.6%

Using recent, clean and environmentally sensitive extraction techniques because of concentrating total extract.

Techniques for extended-term Preservation of the extract in not so fast gel capsules, which are easily ingested, ~ the agency of children and adult alike, as well can be widely distributed due to slack shelf life and basic storage requirements

Using techniques because increasing the resident time of the anti-malarial in a human visible form.

A cure based on the above criteria has been developed and is popularly awaiting clinical trials.

Article Source: http://EzineArticles.com/?dexterous=Virender_Kumar_Bhogal

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