Gout is a debilitating malady that can cause chronic pain, incapability, or chronic renal failure, but it is an easy disease control provided they aver a healthy lifestyle and compliance by therapy.
The treatment for reducing levels of uric pungent tolerated provided that, should be maintained in favor of long periods, to reduce the let fall crystals, and may even be forgiveness.
The treatment is mainly based adhering four operations:
Change of lifestyle
Pharmacological Treatment
Rehabilitation Treatment
Surgical management
1) Change of lifestyle
The diet should have ing balanced and is not necessary to abstract any food in particular.
Foods laughable in uric acid precursors and that should have existence taken with caution are the pork and game, viscera of animals, meats, canned bob, seafood, coffee, tea, chocolate and alcoholic beverages - especially beer.
In corpulent patients, it is preferable a in a condition calorie diet to control not sole of the droplet, but also the violent weight and other metabolic.
Should be avoided precipitating factors of seizures, including capable of intensification efforts, exposure to heat, infection, nutrition and alcohol abuse.
It should start a program of exercise tailored to the indulgent's ability to control weight and improve muscle and commissure mobility.
Unless contraindicated for other therapeutical reasons, it is beneficial abundant intake of shed (2-3 liters per day).
2) Pharmacological handling
The treatment of crises should subsist done with colchicine, and possibly anti-fiery corticosteroid. The corticosteroids may be taken vocally, by intramuscular injection or injected in a straight course into the involved joint.
In the long-winded term, drugs that are regulators of the reduction by evaporation of uric acid are allopurinol and uricosuric (probenecid and sulfinpyrazone, not available in Portugal). Other drugs are heart studied for the same purpose of the same kind with the febuxostat, but this is not besides available.
The urate oxidase (uricase) is each enzyme found in most animals unless not in humans, which degrades urate allantoin in a ultimate particle more soluble and more readily excreted in the urine. Uricase (extracted from a fungus Aspergillus flavus designated) has been used in more countries for the treatment of bitter hyperuricemia and refractory, usually associated by malignancy. Because it is an enzyme recognized similar to foreign by the body, the immune response uricase will rise, causing the damage of their long-term efficacy and may likewise trigger allergic reactions.
Some biotech traits - of that kind as infliximab, anakinra and the canakinumab, are vital principle studied for use in the manipulation of inflammatory crises.
3) Rehabilitation Treatment
The renewal treatment is essential when there are consequences associated through inflammation and progressive joint destruction. Should have existence prescribed by a doctor who specializes, vexation into account the characteristics of both patient.
4) Surgical treatment
Surgical method of treating is intended to correct or put back joints damaged by disease.
Sometimes, which time tophi are bulky and cause functional tumult or aesthetic, may be removed by surgery.
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