Resveratrol has become a popular and widely used supplement in recent years as study after study found new health benefits, from cardiovascular health to life extension. It can lower high blood pressure, reduce fat deposits in the arteries, reduce inflammation and reduce insulin resistance, which can reduce diabetes risk. Recent research has shown it may also prevent or reduce the risk of Alzheimer's disease.
Most of the publicity has centered on the ability of resveratrol to extend life. Calorie restriction causes animals, from mice to humans, to live longer. Studies have shown resveratrol stimulates the production of a protein called SIRT-1, which help extend lifespans. SIRT-1 is one of a group of proteins called sirtuins, which help regulate metabolism.
Resveratrol is also a powerful antioxidant which can help protect brain cells from toxic amyloid plaque, believed to be a leading cause of Alzheimer's disease. Rseveratrol also boosts the energy output of mitochondria, the energy producers within our cells, helping them to withstand amyloid. In addition, it can help neutralize and remove amyloid plaque from the brain even after it has been deposited, leading scientists to speculate that it could be helpful in reversing cognitive impairment.
Scientist at MIT have shown that sirtuins may be able to prevent or suppress Alzheimer's disease. They found mice who produced more of the SIRT-1 sirtuin protein, which is stimulated by resveratrol, were less likely to develop amyloid plaques associated with Alzheimer's.
What is resveratrol?
Resveratrol is a polyphenol found naturally in many plants, such as blueberries, grapes, peanuts and Japanese knotweed. In nature, it acts as a plant antibiotic, protecting plants from disease, infection and injury. In addition to it's many other health benefits, it has been shown to block cancer growth. Studies have shown it works with breast, colon, prostate and thyroid cancers by blocking the activation of a protein (NF-kb).
Resveratrol shows great promise in both extending life through it's ability to mimic caloric restriction and to reduce the risks of aging-related diseases, such as Alzheimer's, cancer and heart disease.
How much do you need?
Studies have shown that as little as 20 mg can be beneficial, but most supplements provide 100-250 mg. Red wine is another source of resveratrol, but you would have to drink over 100 glasses of wine to equal the benefits of just one 100 mg capsule! Be sure to purchase trans-resveratrol, the most biologically active form of resveratrol.